Course Description

Central concepts in regenerative medicine are explored, with a focus on the preclinical development of stem cell therapies. Translational fundamentals include clinically applicable stem cell isolation procedures, methods for stem cell expansion in vitro, and development of models to test the regenerative functions of human stem cells after xenotransplantation into immunodeficient mice. The course will focus on current uses of stem cells for the treatment of human hematopoietic disorders, ischemic vascular diseases, diabetes, and diseases of neuroinflammation and cancer.

Instructors

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Dr. David Hess

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Dr. Sean Cregan

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Dr. John Diguglielmo

Prerequisites/Antirequisites

Suggested Prerequisites

Physiology 3120 and Physiology 3140A

Delivery Method

Asynchronous pre-work and in-person lecture components

Number of Seats

42 (based on 2022 SQCT data)

Grade Breakdown

Blog assignment / discussion forum: 15%

Midterm: 35%

Final Exam: 50%

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Frequency + duration of lectures/labs/tutorials:

2 hours/week lectures

Textbook (and associated cost?)

No textbook

SQCT Snapshot

Expected Grade Breakdown

A (4/5)

B (1/5)

Mean Course as Learning Experience Out of 7 (± SD)

6.6 ± 0.55

Response Rate

12% of students (5/42)

Syllabus

Physiol-4520b-Syllabus-FW24.pdf